- Zeomic and antimicrobial-related terminology
- Antimicrobial agent and antimicrobial test terminology
- Virus terminology
- Odor-eliminating test terminology
- Test terminology
- Approval/license and certification terminology
Terminology: Dermal Sensitization Test (Mandatory SIAA Test Item)
The objective of this test is to detect delayed allergic reaction (Type IV allergy) by means of a one-time application of the test substance to the skin and allowing it to be absorbed. Immunogenicity is acquired in the body so that T-lymphocytes will recognize it and cause an allergic reaction when they come into contact with the same immunogen again.
This method is generally called the ‘Maximization Method.’ Using guinea pigs as test animals, the test substance is administered under the skin at three sites in a shaved area on the back. The test substance is administered again one week later to evaluate the presence of eczema or edema.
[Test Results for Zeomic]
There was no eczema or edema of the skin in the tested sites, and thus it was determined that Zeomic has no dermal sensitization qualities (negative).